Significant side effects could be additional likely in older Older people and those who are overweight, malnourished, or debilitated.

Although getting acetaminophen and codeine phosphate tablets Usually do not: Push or run significant machinery, until finally you know how acetaminophen and codeine phosphate tablets affect you. Acetaminophen and codeine phosphate tablets may make you sleepy, dizzy, or lightheaded.

Instruct patients to search for acetaminophen or APAP on package labels and never to make use of multiple item which contains acetaminophen. Instruct people to hunt health-related notice right away on ingestion of more than 4,000 milligrams of acetaminophen on a daily basis, even when they come to feel well.

Acetaminophen and codeine phosphate tablets need to be prescribed only by healthcare experts who are educated about using opioids and the way to mitigate the linked hazards.

Normally talk to your healthcare company to be sure the information exhibited on this website page relates to your own situations.

Speedy discontinuation has also been connected to attempts to search out other sources of opioid analgesics, which can be perplexed with drug-searching for for abuse.

The protection and performance of acetaminophen and codeine phosphate tablets in pediatric patients beneath the age of 18 have not been recognized.

Extensive-expression use of opioid medication may have an impact on fertility (ability to have little ones) in Males or Women of all ages. It is far from regarded regardless of whether opioid consequences on fertility are long lasting.

Adults must not choose more than 4000 milligrams (four grams) of acetaminophen every day. Individuals with liver difficulties and children should choose considerably less acetaminophen. Ask your doctor or pharmacist how much acetaminophen is Safe and sound to acquire.

Advise individuals and caregivers that perhaps deadly additive consequences may happen if acetaminophen and codeine phosphate tablets are utilised with benzodiazepines or other CNS depressants, website which include Liquor, instead of to use these medication concomitantly Except if supervised by a Health care service provider (see WARNINGS and Safeguards, Drug Interactions).

Individually titrate acetaminophen and codeine phosphate tablets to the dose that gives ample analgesia and minimizes adverse reactions. Constantly reevaluate patients acquiring acetaminophen and codeine phosphate tablets to assess the maintenance of agony Regulate, indications and signs and symptoms of opioid withdrawal, as well as more info other adverse reactions, as well as reassessing for the event check here of habit, abuse, or misuse (see WARNINGS).

Healthcare vendors are strongly encouraged: to accomplish a REMS-compliant schooling program; counsel sufferers and/or here their caregivers, with every prescription, on Safe and sound website use, significant dangers, storage, and disposal; emphasize to clients and their caregivers the necessity of looking through the Medication Guide anytime it can be supplied by their pharmacist; and consider other instruments to improve patient, house, and community basic safety.

Appraise individuals obtaining acetaminophen and codeine phosphate tablets and any CYP3A4 inhibitor or inducer for indicators and signs or symptoms that could replicate opioid toxicity and opioid withdrawal when acetaminophen and codeine phosphate tablets are utilized along with inhibitors and inducers of CYP3A4 (see PRECAUTIONS, Drug Interactions).

Get health care enable at once When you've got any pretty serious Unwanted side effects, such as: fainting, seizure.